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Treat Hereditary Angioedema (HAE) swells with RUCONEST

Why RUCONEST

RUCONEST Patients

Patients featured on this page have been compensated to share their stories. Individual results may vary.

When HAE attacks happen, you need a 
treatment you can count on.

In the primary clinical study, the median time to beginning of symptom relief was 90 minutes vs 152 minutes with placebo1

1. RUCONEST. Prescribing Information. Pharming Healthcare, Inc; 2020.

~9 of 10 patients achieved symptom relief with just 1 dose of RUCONEST at 50 U/kg (n=44) in the primary clinical study1

1. RUCONEST. Prescribing Information. Pharming Healthcare, Inc; 2020.

Reliable
 Dosing1*

1. RUCONEST. Prescribing Information. Pharming Healthcare, Inc; 2020.

Dose

1

97% of HAE attacks needed 
JUST 1 DOSE of RUCONEST

Rapid SWELL
 Resolution2†

2. Riedl MA, et al. Adv Ther. Published online May 20, 2026. doi:10.1007/s12325-026-03625-0

Hours

4.5

Median time to complete attack resolution was 4.5 hours with RUCONEST

Lasting
 Relief3‡

3. Bernstein JA, Relan A, Harper JR, Riedl M. Sustained response of recombinant human C1 esterase inhibitor for acute treatment of hereditary angioedema attacks. Ann Allergy Asthma Immunol. 2017;118(4):452-455. doi:10.1016/j.anai.2017.01.029

Days

3

RUCONEST stopped 93% of attacks for at least 3 days

HAE, hereditary angioedema; OLE, open-label extension; PGI-S, Patient Global Impression of Severity; RCT, randomized clinical trial; VAS, visual analog scale.

*50 U/kg (max 4200 U); OLE phase (n=44; 170 attacks).1

1. RUCONEST. Prescribing Information. Pharming Healthcare, Inc; 2020.

†Researchers later reviewed completed RUCONEST clinical studies to see when symptoms were completely gone including 108 patients across 3 RCTs evaluating RUCONEST (RUCONEST arm, n=48, 50 U/kg [max 4200 U]; placebo arm, n=60). Time to complete attack resolution was defined as a PGI-S category of “none” within 24 h of treatment administration. A bookmarking study was used to map VAS scores from the original RUCONEST RCTs to the corresponding PGI-S category.2

‡Researchers later reviewed completed RUCONEST clinical studies to see when symptoms were completely gone involving 127 patients aged >12 years who were treated with RUCONEST 50 U/kg (max 4200 U) for acute attacks of HAE. Data for 72 hours were available for 68 of 127 patients (280 attacks).3

RUCONEST is my go-to. I don’t feel the anxiety of having an attack. I can do the things I love knowing I have RUCONEST to back me up.”

– Alex, a real RUCONEST patient

RUCONEST checks all the boxes. It gives me the confidence to self-administer and the one-and-done dosing and patient support have made a real difference.”

– Debbie, a real RUCONEST patient

It’s incredible to realize you can get back to things you love with the right preparation and medication. The difference it’s made has meant the world to me.”

– Noah, a real RUCONEST patient

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Learn How

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